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Semax

Price range: $39.00 through $69.00

Semax is a synthetic heptapeptide derived from the 4–10 fragment of adrenocorticotropic hormone (ACTH). Its sequence is Met-Glu-His-Phe-Pro-Gly-Pro, with a molecular formula of C38H54N12O9 and a molecular weight of approximately 826.92 g/mol (CAS 80714-61-0). First described in the late 1980s, Semax is modified with a Pro-Gly-Pro tripeptide tail, a structural feature designed to resist cleavage by prolyl endopeptidases and enhance peptide stability compared to the native ACTH fragment.

Supplied as a white lyophilized powder, Semax dissolves readily in water and is intended exclusively for controlled laboratory research applications.

For research use only. Not approved for human or animal consumption.

Description

Semax is a synthetic heptapeptide consisting of seven amino acids with the sequence Met-Glu-His-Phe-Pro-Gly-Pro. First described in the late 1980s, it is derived from the 4–10 fragment of adrenocorticotropic hormone (ACTH) and modified with a Pro-Gly-Pro tripeptide tail to enhance stability and resist enzymatic degradation compared to the native ACTH fragment.

The peptide has a molecular formula of C37H51N9O10S (free acid form) and a molar mass of approximately 813.93 g/mol (826.92 g/mol as the acetate salt). Its CAS number is 80714-61-0. Semax is supplied as a white to off-white lyophilized powder that dissolves readily in water. The Pro-Gly-Pro extension is a structural motif commonly used in peptide chemistry to protect against prolyl endopeptidase cleavage.

For research use only. Not approved for human or animal consumption.

Additional information

Select MG	5mg, 10mg

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